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Abbreviated Impactor Measurement (AIM) Equipment
The Abbreviated Impactor Measurement (AIM) Method implies using a shorter process to characterize aerodynamic size
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The Abbreviated Impactor Measurement (AIM) Method implies using a shorter process to characterize aerodynamic size. It has been promoted as an alternative to the labor-intensive full resolution cascade impactor methodology for APSD (aerodynamic particle size distribution) testing.
Using an AIM methodology for early stage development has become increasingly popular as both OINDP device and drug companies look for ways to shorten drug development. This technology has traditionally been limited to early development signals indicating rough drug particle size, and this equipment is still intended to categorize the entire dosage for effective mass balance exercises.
More recently the AIM methodology has been expanded into full submissions to the FDA for approval and the resulting ongoing quality control testing. Drug manufacturers use abbreviated impactors such as the FSA (Anderson version), the FSI (fast screening impactor), and the rNGI (reduced NGI) as tools to significantly reduce the time and effort spent in test collection and analysis. By using the correlating device, the results can easily be extrapolated and transferred to the full device (i.e. FSA results are transferred to the Andersen Impactor).
MSP carries a variety of AIM Methodology equipment, including the FSA, FSI, and rNGI. These products are also featured in the Copley Catalog, and part numbers for the Copley Catalog are included in the chart below.
Mensuration and calibration are imperative in pharmaceutical testing, and is recommended by the FDA (Food and Drug Administration), USP (United States Pharmacopeia), and GMP (Good Manufacturing Practices).
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MSP provides calibration and mensuration services, as well as calibration contracts and extended warranties as part of our QualityGuard™ program.
Each instrument model is unique, please refer to the model-specific service documentation below for details on what each package includes:
Contact the MSP Sales Team (MSPSales@tsi.com) to learn more and order your calibration contract and/or extended warranty by filling out the form below. You can also refer to our QualityGuard ordering brochure for additional detail, including how to ship your equipment to MSP.