In Vitro – In Vivo Correlation IVIVC Equipment

In Vitro – In Vivo Correlation (IVIVC) links in vitro properties of a dosage form to its in vivo performance, essential for generic drug development. While FDA guidance is limited, interest in IVIVC is increasing.

Our IVIVC equipment features anatomically representative mouth and throat geometries, like the Alberta Idealized Throat (AIT), alongside advanced breathing simulators that replicate diverse patient breathing patterns, such as those in COPD or asthma. This innovative design allows for customizable inhalation and exhalation profiles, ensuring accurate drug delivery representation.

Integrating IVIVC methods into development processes reduces costs and risks in clinical trials, making it a valuable investment for Orally Inhaled and Nasal Drug Products (OINDP). Our solutions enhance this critical aspect of pharmaceutical development for better therapeutic outcomes.